Senior Lecturer · UiTM · AuRIns
Synthetic organic & medicinal chemist designing bioactive heterocyclic scaffolds and probing enzyme inhibition at the molecular roots of disease.
About
I am a Senior Lecturer at the Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), and a Fellow at the Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Puncak Alam Campus.
I completed my PhD in 2016, publishing over 16 journal articles during candidacy and earning the Anugerah Tuanku Canselor — UiTM's highest graduation honour. After a postdoctoral stint at AuRIns, I joined the Faculty of Applied Sciences as Senior Lecturer.
My research combines classical bench chemistry with modern computational drug discovery to identify potent leads against metabolic, neurodegenerative, and infectious diseases.
Senior Lecturer, Faculty of Applied Sciences, UiTM Shah Alam. Fellow at AuRIns, Puncak Alam.
UiTM's highest graduation honour, awarded for outstanding academic and research achievement during PhD candidacy.
3,542 Scopus citations · 3,982 Google Scholar citations across enzyme inhibition, heterocyclic chemistry, and computational drug discovery.
AutoDock, QSAR, DFT, MD simulations, and CYP3A4 classifier modelling fully integrated alongside experimental synthesis.
Research
Spanning synthetic chemistry, biological evaluation, and in silico modelling — discovering potent leads against metabolic and neurodegenerative diseases.
Enzyme Targets
Key inhibition targets across the research portfolio
Key Scaffolds
🔷 Bisindolylmethane — antihyperglycemic, anticancer, antileishmanial
🌸 Flavone / Chalcone — α-glucosidase, CA-II, 15-LOX inhibition
🔵 Indole — urease, β-glucuronidase, α-amylase inhibition
⬡ Oxadiazole / Triazole — multi-target enzyme inhibition
🟤 Thiadiazole / Thiourea — urease, glycation, DPPH scavenging
Taha, M. et al. — Synthesis and molecular docking. Scientific Reports, 16(1), 2944.
Munir, Z., Imran, S. et al. — Piperidine–triazole library vs AChE, BChE, urease. ACS Omega, 10(41), 48586.
Ayub, M., Imran, S. et al. — Design, synthesis, computational studies. ACS Omega, 10(39), 45191.
Imran, S. et al. — 22 analogues, IC₅₀ 0.60–30.90 μM, outperforming thiourea standard. J Biomol Struct Dyn, 40(18).
Imran, S. et al. — New flavone series via nucleophilic substitution of 3'-hydroxyflavone. Chem Biol Drug Des, 87, 361–373.
Imran, S., Taha, M., Ismail, N.H. — Comprehensive pharmacological review. Curr Med Chem, 22(38).
Teaching
Making complex pharmacokinetic and chemical principles accessible, relevant, and engaging for pharmacy and applied science students.
CMT667
Advanced pharmacokinetic principles — ADME modelling, quantitative analysis, and clinical applications for postgraduate pharmacy students.
Medicinal Chemistry
Structure–activity relationships, lead optimisation, and the molecular basis of drug action bridging classical theory and rational drug design.
Chemistry
Mechanism reactions involving carbonyl compounds. Application of Aldol, Claisen, Wittig, and Robinson Annulation reactions to form heterocyclic compounds.
Computational
Practical training in molecular docking, virtual screening, and QSAR — equipping students with computational tools used in modern drug discovery.
Spectroscopy
NMR, mass spectrometry, and spectroscopic techniques for structural elucidation in synthetic and pharmaceutical research contexts.
Laboratory
High-field NMR spectroscopy supporting structural characterisation in medicinal chemistry, natural product research, and pharmaceutical analysis at UiTM.
Atta-ur-Rahman Institute for Natural Product Discovery
Universiti Teknologi MARA, Puncak Alam, Selangor
Contact
Whether you're a collaborator, student, or fellow researcher — reach out through any of the channels below.